Sunday, October 6, 2013

FRCR Oncology Part 1: Pharmacology 3 (3 questions)

1. Which of the following chemotherapy drug is likely to be toxic to gonads?
a. Adriamycin
b. Vinblastine
c. Paclitaxel
d. Procarbazine

2. High dose chemotherapy given prior to stem cell transplant may be associated with gonadal failure. Risk is least with the use of
a. Busulfan + cyclophosphamide
b. Cyclophosphamide + TBI
c. Ifosfamide +carboplatin+ Etoposide
d. Fludarabine + ATG

3. Which one of the following is an accurate definition of the sensitivity of a screening test?
a. The percentage of screening tests that are positive
b. The percentage of screening tests that are negative among patients who remain unaffected by the condition of interest after screening
c. The percentage of screening tests that are positive among patients who remain unaffected by the condition of interest after screening
d. The probability of a diagnosis of the condition of interest after a positive screening test